AMPROLINVET 500

AMPROLINVET 500
AMPROLINVET 500
Ingredients: hydrochloride amprolium, Additive agents: tartaric acid, sucrose
Application: Oral
Type of formulation: Coccidiostatic

Description

Powder of white up to dark yellow color

Composition

1 g of preparation contains active agent:

hydrochloride amprolium - 500 mg.

Additive agents: tartaric acid, sucrose.

Pharmacological properties

ATCvet QP51, antiprotozoal  veterinary drug (QP52AХ09, amprolium)

Active agents of the drug, hydrochloride amprolium, has a wide range of anticoccidial effect and is effective in respect of chickens eimeriaEimeria tenella, E. necatrix, E. acervulina, E. praecox, E. maxima, E. brunetti, E. mitis; turkey cocks - E. adenoides, E. gallapavonis, E. meleagrimitis; pheasants - E. phasiani, E. colchici, E. Duodenalis.

Anticoccidial effect of amprolium is provided by the fact that its chemical structure is close to thiamine (vitamin  В1), required for vital activity of eimeria. In cells of parasites amprolium disturbs carbohydrate metabolism that leads to their death.

We know that, in general, hydrochloride amprolium inhibits progress of eimeria at the stage of the first and the second schizogony generation and is an antagonist of vitamin В1. It does not almost penetrate through cell membranes of mucous tunic of poultry and mammals’ intestines, therefore, the drug is not actually toxic if to use it according to therapeutical doses. The general part of amprolium (up to 97%) is removed from the organism in unchanged form. The preparation does not inhibit formation of anticoccidial immunity, is compatible with vitamins and food additives that are used in livestock and poultry farming.

Use

Treatment and prophylactic treatment of chickens, turkey cocks and pheasants in case of eimeria affection.

- chickens (broiler chicken, replacement chicks): Eimeria  tenella, Е. necatrix, Е. acervulina, Е. praecox, Е. maxima, Е. brunettі, Е. mitis;

- turkey cocks: Е. adenoeides, Е. gallapavonis, Е. meleagrimitis;

- pheasants: Е. phasiani, Е. colchici, Е. duodenalis.

Dosage

The preparation shall be added to potable water according to the doses:

Broilers:

 for preventive purposes  –  250 g of drug per 1000 l of potable water (125 mg of hydrochloride amprolium per 1 l of water) starting from 3 - 5 days age during the breeding period excluding it from the food allowance three days before slaughter;

treatment – 500 g of the drug per 1000 l of potable water (250 mg of hydrochloride amprolium per 1 l of water) during 3-5 days.

Replacement chickens:

for preventive purposes  –  250 g of drug per 1000 l of potable water (125 mg of hydrochloride amprolium per 1 l of water) starting from 3 - 5 days age up to the sixteen weeks age;

treatment – 500 g of the drug per 1000 l of potable water (250 mg of hydrochloride amprolium per 1 l of water) during 3-5 days.

 Turkey cocks, pheasants:

for preventive purposes – 250 g per 1000 l of potable water (125 mg of hydrochloride amprolium per 1 l of water) starting from 1-day age up to 12 weeks age or up to the end of the period during which eimeriosis threat is present;

treatment – 500 g of the drug per 1000 l of potable water (250 mg of hydrochloride amprolium per 1 l of water) during 3-5 days.

During the period of medioprophylactic measures the solution of the preparation shall be the only source of potable water for poultry.

After dilution in potable water the preparation can be used during 16 hours.

Contraindications

Do not use for poultry with hypersensitivity to hydrochloride amprolium!

Do not use for debilitated, fragile and ill poultry!

Warning

Poultry slaughter for meet shall be allowed in 3 days after the last preparation use. In case of slaughter before the specified term the meat shall be fed to unproductive animals or utilized depending on the comment of a doctor in the field of veterinary medicine.

Pharmaceutical form and presentation

Packages of polyethylene film or any other polymer film of 1 g, 2 g, 5 g, 10 g, 50 g, 100 g, 500 g and 1 kg each.

Polymeric containers of 500 g and 1 kg each.

Storage

The drug shall be stored in a place protected from light at the temperature of 5 - 25 °С in the original package on racks or shelves (not more than three ones).

Self life

2 years. After dilution in potable water the preparation can be used during 16 hours.

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