ANTI-TOX FORTE (feed mixture)
| Ingredients: | Enzymes, Bacillus bacteria, corn starch, lactose |
| Application: | Orally with food |
| Type of formulation: | feed mixture |
Description
Powder from yellowish to brown in colour
Composition
1 g of feed mixture contains:
Enzymes produced by bacteria of the genus Bacillus inactivate a broad spectrum of mycotoxins: AFB, ZEA, DON, T-2, FUM, OTA:
- enzyme deactivating aflatoxins AFB — not less than 20 000 IU/g;
- enzyme deactivating zearalenone ZEA — not less than 15 000 IU/g;
- enzyme deactivating FUM — not less than 40 000 IU/g;
- enzyme degrading vomitoxin DON — not less than 50 000 IU/g;
- enzyme degrading toxin T2 — not less than 40 000 IU/g;
- enzyme degrading OTA — not less than 30 000 IU/g.
- Bacillus licheniformis — at least 2,0*109 CFU/g
- Bacillus subtilis — at least 3,0*109 CFU/g
- corn starch — 0,10 g;
- lactose — 0,05 g.
Moisture content not more than 10 %.
Pharmacological Properties
The feed mixture ANTI-TOX FORTE belongs to enzyme products of specific action and fourth-generation probiotics and contains spore-forming bacteria Bacillus licheniformis, Bacillus subtilis.
ANTI-TOX FORTE is an entirely biological product containing enzymes capable of degrading all major mycotoxins relevant for animals, including AFB, ZEA, DON, T-2, FUM, OTA and others. The efficacy reaches 99.8% for animals and poultry.
The feed mixture ANTI-TOX FORTE may improve immune function and partially support liver cell recovery. Clinical signs may be reduced.
Auxiliary components of the feed mixture ANTI-TOX FORTE are Bacillus subtilis and Bacillus licheniformis (live bacteria). Primary and secondary metabolites of these live bacteria are small protein molecules with a detoxifying effect. The feed mixture acts by cleaving epoxy groups of mycotoxins and breaking toxic substances down into non-toxic metabolites; it can replace 50% of the probiotic dose.
Bacillus subtilis is a spore-forming bacterium that suppresses the growth of pathogenic Gram-positive and Gram-negative bacteria through competitive exclusion without causing resistance. It produces lysozyme and peptides with antibiotic properties in the intestine, as well as a large number of enzymes.
Bacillus licheniformis is a spore-forming bacterium that synthesizes vitamins in the digestive tract — vitamin K, riboflavin, and folic acid. It helps maintain the acid-base balance in the large intestine, produces lactic acid, and promotes nutrient absorption. It suppresses the growth of pathogenic microorganisms and stimulates the growth of lactobacilli.
The symbiosis of these bacteria improves the condition of the intestinal microflora and reduces the risk of bacterial diseases through the natural displacement of opportunistic bacteria, stimulating the proliferation of lactic acid bacteria. The high enzymatic activity of these bacteria supports digestive processes and improves feed digestion and absorption of beneficial substances. By stimulating the phagocytic activity of monocytes and neutrophils, enhancing the functional activity of macrophages, inducing endogenous interferon, and increasing the gamma-globulin fraction in the blood, the non-specific resistance of the organism is enhanced.
Indications
The feed mixture ANTI-TOX FORTE may help prevent diseases of poultry and animals caused by mycotoxins.
ANTI-TOX FORTE may also be used for therapeutic purposes, for degradation of mycotoxins and removal of toxins, for increasing the natural resistance of the organism and the intensity of immunity during and after vaccinations, and for protecting the animal body against the effects of stress of various origins.
Dosage and Administration
Recommended doses of the feed mixture when used against different mycotoxins at different levels, as well as the results of the control effect (AS: absolutely safe; RS: relatively safe, because cumulative poisoning is possible; OI: obvious improvement), are given in the following tables.
Dosage of the feed mixture ANTI-TOX FORTE for mycotoxins AFB, T-2, FUM, OTA:
Pigs, broiler chickens:
|
With feed |
0-10 ppb mycotoxin
concentration |
10-20 ppb mycotoxin
concentration |
20-30 ppb mycotoxin
concentration |
30-40 ppb mycotoxin
concentration |
≥ 40 ppb mycotoxin
concentration |
|
120 g/ton |
93% (AS) |
89% (AS) |
82% (RS) |
75% (OI) |
1500 g/ton |
|
200 g/ton |
97% (AS) |
93% (AS) |
87% (AS) |
77% (RS) |
|
|
400 g/ton |
99% (AS) |
96% (AS) |
92% (AS) |
83% (AS) |
Cattle: 30 g - 50 g of feed mixture per 1 ton of compound feed.
Dosage of the feed mixture ANTI-TOX FORTE for mycotoxin ZEA:
Pigs, broiler chickens:
|
With feed |
0-100 ppb mycotoxin concentration |
100-200 ppb mycotoxin concentration |
200-300 ppb mycotoxin
concentration |
300-500 ppb mycotoxin concentration |
500-1000 ppb mycotoxin concentration |
≥ 1000 ppb mycotoxin concentration |
|
120 g/ton |
89% (AS) |
86% (AS) |
78% (RS) |
70% (OI) |
52% (OI) |
1500 g/ton |
|
200 g/ton |
93% (AS) |
91% (AS) |
87% (AS) |
72% (RS) |
60% (OI) |
|
|
400 g/ton |
96% (AS) |
93% (AS) |
89% (AS) |
80% (AS) |
69% (OI) |
Cattle: 30 g - 50 g of feed mixture per 1 ton of compound feed.
Dosage of the feed mixture ANTI-TOX FORTE for mycotoxin Vomitoxin (DON):
Pigs, broiler chickens:
|
With feed |
0-1000 ppb mycotoxin
concentration |
1000-1500 ppb mycotoxin
concentration |
1500-2000 ppb mycotoxin
concentration |
2000-3000 ppb mycotoxin
concentration |
≥ 3000 ppb mycotoxin
concentration |
|
150 g/ton |
81% (AS) |
76% (AS) |
72% (RS) |
57% (OI) |
1500 g/ton |
|
200 g/ton |
86% (AS) |
80% (AS) |
86% (RS) |
64% (OI) |
|
|
400 g/ton |
91% (AS) |
86% (AS) |
81% (AS) |
69% (RS) |
Cattle: 30 g - 50 g of feed mixture per 1 ton of compound feed.
Contraindications
Not established.
Warnings
When handling the feed mixture, generally accepted sanitary and hygienic standards and rules of production practice must be observed. Use only as intended.
Packaging
Packs of 1 kg and bags of 5, 10, 20, and 25 kg.
Storage
Store in a dry, dark place at a temperature from 5ºС to 30°С and relative air humidity not exceeding 75%.
Shelf Life
2 years.