MEDICYLATE® (granules)

Granules ranging in colour from light yellow to light brown.

1 g of the product contains the active substance:

- bacitracin methylene disalicylate — 150 mg.

Excipients: calcium carbonate, maize starch.

ATCvet classification code QJ01 — antibacterial veterinary medicinal products for systemic use. QJ01XX10 — Bacitracin.

Bacitracin methylene disalicylate is a cyclic polypeptide antibiotic. It exerts a bactericidal effect against Gram-positive bacteria (Staphylococcus aureus, Streptococcus spp., Enterococcus spp., Clostridium spp., Corynebacterium spp.). It inhibits bacterial cell wall synthesis by suppressing the regeneration of phospholipid receptors involved in peptidoglycan synthesis.

When ingested with feed, bacitracin methylene disalicylate suppresses the growth of pathogenic microflora in the gastrointestinal tract. As a result, digestive and metabolic processes in the animal are activated. Bacitracin methylene disalicylate is virtually not absorbed from the gastrointestinal tract; therefore, it does not accumulate in organs and tissues, regardless of the duration of administration and the doses applied.

It is excreted from the animal body via faeces.

Treatment of pigeons with clostridiosis caused by microorganisms (Clostridia spp.) susceptible to bacitracin methylene disalicylate.

Orally, mixed with complete feed at a dose of 0,33–0,66 g of the product per 1 kg of feed, corresponding to 50–100 mg of bacitracin methylene disalicylate per 1 kg of feed, daily for 7 days.

Hypersensitivity to bacitracin methylene disalicylate.

Do not use in food-producing animals!

Do not use for prophylactic purposes!

The product is recommended for use only after antimicrobial susceptibility testing (AST) of the causative microorganisms to bacitracin has been performed.

Do not use concomitantly with strong oxidising agents.

The product should be used only after a benefit/risk assessment has been established by a veterinarian.

General rules of personal hygiene and safety precautions applicable to the handling of medicinal products must be observed during use. All work should be carried out wearing protective clothing and personal protective equipment. In the event of accidental contact with skin or mucous membranes, the product must be immediately washed off with a stream of running water. In the event of contact with eyes, rinse thoroughly with large amounts of running water and seek medical attention.

Bags/pouches of 1, 10, 50, and 100 g.

Store in a dry, dark place, out of reach of children, at a temperature of 5 to 25 °C.

2 years from the date of manufacture.