COMPOSITION
White to light grey rounded tablets
COMPOSITION
PHARMACOLOGICAL PROPERTIES
ATCvet QP52A, antitrematode, antinematode and anticestode veterinary preparations (QP52AS11, albendazole).
The active ingredient of the preparation albendazole belongs to the group of benzimidazoles.
Albendazole mechanism of action is to inhibit protein (tubular) synthesis, resulting in broken receipts and intracellular transport of nutrients and metabolism of substrates of substances (adenosine triphosphate and glucose), and reducing mitochondrial reactions through inhibition of fumeratereductases, resulting in the decrease of glycogen level and death of parasites from exhaustion.
Albendazole also has ovicidal effect (destroys helminth eggs), reduces pasture contamination and places for walking dogs, reduces the probability of reinfection of animals.
Albendazole is used for animals without dieting and the use of laxatives.
INDICATIONS
The prevention and treatment of parasitic diseases caused by mature forms of larvae and eggs of gastrointestinal and pulmonary nematodiasis (roundworms), cestodiasis (tapeworms) and trematodiasis for horses, cattle, sheep, goats, pigs, dogs and cats.
Cattle, sheep, goats:
• gastrointestinal nematodiasis: Haemonchus contortus, Ostertagia spp., Trichostrongylus axei, Trichostrongylus colubriformis, Cooperia oncophora, Oesophagostomum radiatum, Nematodirus helvetianus;
• pulmonary nematodiasis: Dyctyocaulus viviparus;
• cestodiases (tape worms): Moniezia expansa;
• trematodiases: Fasciola hepatica (adults).
Pigs:
• gastrointestinal nematodiasis: Ascaris suum, Oesophagortomum spp., Trichocephalus spp., Strongyloides spp., Metastrongylus spp.
Horses:
• nematodiasis: Parascaris eguorum, Strongylus vulgaris, S.eguinus, Oxyuris egui.
In carnivores (dogs, cats):
• gastrointestinal nematodiasis: Toxocara spp., Toxascaris spp., Uncinaria spp., Ancylostoma spp., Trichocephalus spp.,
• cestodiasis: Taenia solium, Dipylidium caninum, Diphyllobothrium latum;
• trematodiasis: Opisthorchis felineus.
CONTRAINDICATIONS
PRECAUTIONS
DOSAGE
The preparation is administered orally one time without dieting in the following dosage:
Dose, g/kg | Dose, g/kg | Dose of the AI , mg/kg of b.w. | Dose, tablet/kg of b.w. |
Cattle | Nematodiasis | 7.5 | 1 /50 |
Cestodiasis | 7.5 | 1 /50 | |
Trematodiasis | 10.0 | 1 / 35-40 | |
Horses | Nematodiasis | 7.5 | 1 /45-50 |
Cestodiasis | 7.5 | 1 /45-50 | |
Goats and sheep | Nematodiasis | 5.0 | 1 /70 |
Cestodiasis | 5.0 | 1 70 | |
Trematodiasis | 10.0 | 1 /35-40 | |
Pigs | Nematodiasis | 10.0 | 1 /35-40 |
Dogs, cats | Nematodiasis | 25.0 | 1 /15 |
Cestodiasis | 25.0 | 1 /15 | |
Trematodiasis | 25.0 | 1 /15 |