AMOXIVET 15% LA (suspension for injection)

AMOXIVET 15% LA (suspension for injection)
AMOXIVET 15% LA (suspension for injection)
Ingredients: Amoxicillin trihydrate
Application: Injecting
Type of formulation: Antibiotic
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CHARACTERS

An oily, white to yellowish suspension. It is layered when stored.

COMPOSITION

Each 1 mL contains:
Amoxicillin trihydrate - 150 mg 

PHARMACOLOGICAL ACTION

Amoxicillin belongs to the group of β-lactam antibiotics. It blocks the synthesis of cellular walls of the bacteria, inhibits the activity of the enzyme transpeptidase and carboxypeptidase, causes a disturbance of the osmotic balance, leading to the death of the microorganisms during its growth.

The preparation is active against Gram-positive microorganisms (Bacillus antracis, Cloctridium spp., Corynebacterium spp., Erysipelothrix rhusiopathiae, Streptococcus spp., Staphylococcus spp., Leptospira spp., Listeria monocytogenes) and Gram-negative microorganisms (Actinobacillus spp., Bordetella bronchiseptica, Fusobacterium spp., Haemophilus spp ., Moraxella spp., Pasteurella spp., Proteus mirabilis, Salmonella spp.) and other pathogens that are susceptible to amoxicillin.

After intramuscular administration amoxicillin is rapidly absorbed into the blood and is distributed in most tissues and body fluids. During the  meninges inflammation concentration of the drug in cerebro spinal fluid may be up to 30-60% of the concentration in serum.

Amoxicillin is deduced unchanged mainly through kidneys by tubular secretion, but a small portion is metabolized by hydrolysis to inactive the penicillin acid and excreted in the urine.

INDICATIONS

Treatment of calves under 6 weeks old, pigs, sheep, goats and poultry (chickens, broilers, pullets, turkeys, ducks, geese) sick with septicemia, meningitis, erysipelas, arthritis, arthritis, as well as the diseases of the alimentary canal (gastritis, enteritis , peritonitis), respiratory system (tonsillitis, tracheitis, pneumonia, bronchitis, rhinitis, sinusitis, pneumonia), and genitourinary system (nephritis, pyelitis, pyelonephritis, urethritis, urocystitis, metritis, mastitis) and skin (dermatitis) caused by pathogens susceptible to amoxicillin.

DOSAGE AND ADMINISTRATION

The preparation is administered by intramuscular or subcutaneous injection.

- cattle - 1.0 g of the preparation per 10 kg of body weight;

- sheep, goats - 1.0 g of the preparation per 10 kg of body weight;

- pigs - 1.0 g of the preparation per 10 kg of body weight;

- dogs, cats - 2.0 g of the preparation per 10 kg of body weight;

The course of treatment - 3 - 5 days.
Use the drug every 48 hours for 3-5 days, and the injection itself is repeated in the third and fifth day.
Shake and warm up the drug to 36 °C before use.

CONTRAINDICATIONS

Hypersensitivity to penicillins or other β-lactam preparation groups.
Do not used in rabbits, guinea pigs, hamsters or other small herbivores.
Do not use for animals with impaired renal function.
Do not use concurrently with antibiotics cephalosporins, tetracyclines, macrolides.

PRECAUTIONS

If the dose required more than 20 mL –  it is recommended to divide the dose and administer in several sites.
Animals may only be slaughtered for meat in 14 days of the last use of the preparation; milk is fit for food in 4 days.

HOW SUPPLIED

Vials made of the neutral glass 10, 20 and 100.
Outer packaging – carton box.

STORAGE

Dry, dark, inaccessible to children place at temperature from 5°C to 25°C.
Shelf life – 2 years.
After the first selection from the vial, the preparation should be used within 14 days, provided storage in a dark place at a temperature of 0°C to 5°C.

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