-500x500.jpg "AMPROLINVET (oral solution)")
| Ingredients: | Amprolium Hcl |
| Application: | Oral |
| Type of formulation: | Coccidiostatic |
DESCRIPTION
Oily liquid from light to dark yellow color.
COMPOSITION
PHARMACOLOGICAL PROPERTIES
ATCvet QP51A, preparations against protozoan infections (QP52AX09, amprolium).
Active working substance of the preparation – amprolium hydrochloride, has a wide range of anticoccidioidal action, is effective against coccidia of chickens E. tenella, E. necatrix, E. acervulina, E. praecox, E. maxima, E. brunette, E. mitis; Turkeys - E. adenoeides, gappapavonis E., E. meleagrimitis; pheasants - E. phasiani, E. colchici, E. duodenalis; rabbits - E. stiedae, E. perforons, E. magna; Lambs - E. arloingii, E. Ahsata, E.faurei; calves - E. bovis and E. zurnii.
Anticoccidioidal action of amprolium is caused by its chemical structure similar to thiamine (vitamin B1), which required for life of eimeria. In the cells of parasites, amprolium violates carbohydrate metabolism, which leads to their death.
It is known that amprolium hydrochloride mainly inhibits the development of eimeria on the stage of shizogony of the first and second generation and is an antagonist of vitamin B1. Almost does not penetrate the cell membrane of the intestinal mucosa of birds and mammals, and is practically non-toxic in therapeutic doses. Most part of amprolium (up to 97%) is excreted from the organism unchanged. The preparation does not inhibit the formation of anticoccidioidal immunity, compliant with vitamins and feed additives used in poultry farming.
INDICATIONS
Prevention and treatment of cattle (calves), sheep (lamb), rabbits (rabbits up to 4-5 months old), chickens, turkeys and pheasants with Eimeria lesions:
- cattle (calves) – E. bovis and E. Zurnii;
- sheep (lambs) – E. arloingii, E. ahsata, E. Faurei;
- rabbits – E. stiedae, E. perforons, E. magna;
- chickens – Eimeria teneila, E. necatrix, E. acervulina, E. praecox, E. maxima, , E. brunetti, and E. mitis;
- turkeys – E. adenoeides, E. gallapavonis, E. meleagrimitis;
- pheasants – E. phasiani, E. Colchici, E. duodenalis.
DOSAGE
The preparation is fed with drinking water in the following doses:
Broilers:
prophylactically – 1 ml of the preparation per 1 liter of drinking water (125 mg of amprolium HCl to 1 liter of water) starting from age of 3 – 5 days during the period of raising, excluding from the diet 3 days prior to slaughtering; treatment - 2 ml of the preparation per 1 liter of drinking water (250 mg of amprolium HCl to 1 liter of water) for 5-7 days.
Young chickens:
prophylactically – 1 ml of the preparation per 1 liter of drinking water (125 mg of amprolium HCl to 1 liter of water) starting from the age of 3 – 5 days up to 16 weeks old; treatment – 2 ml of the preparation per 1 liter of drinking water (250 mg of amprolium HCl to 1 liter of water) for 5-7 days.
Turkeys and pheasants:
prophylactically - 1 ml of the preparation per 1 liter of drinking water (125 mg of amprolium HCl to 1 liter of water) starting from the age of 1day up to 12 weeks or before the end of period during which there is a threat of coccidiosis; treatment - 2 ml of the preparation per 1 liter of drinking water (250 mg of amprolium HCl to 1 liter of water) for 3-5 days.
Rabbits:
prophylactically- 2.5 ml of the preparation /10 kg of body weight during a period when there is a threat of coccidiosis; treatment – 5 ml of the preparation /10 kg of body weight for 3-5 days.
Calves under 1 year old and lambs:
prophylactically - 1 ml of the preparation / 10 kg of body weight during a period when there is a threat of coccidiosis; treatment - 2 ml of the preparation / 10 kg of body weight for 5-7 days.