-500x500.jpg "TILMICOVET ® 25%")
| Ingredients: | Tilmicosin Phosphate |
| Application: | oral |
| Type of formulation: | antibiotic |
DESCRIPTION
Oily liquid from light yellow to dark yellow color.
COMPOSITION
PHARMACOLOGICAL PROPERTIES
ATC vet classification code QJ01 - antibacterial veterinary medicines for systemic use. QJ01FA91 - Tilmicosin.
The active ingredient of the preparation is an antibiotic tilmicosin phosphate, semi-synthetic macrolide antibiotic.
Tilmicosin – is a semi-synthetic antibiotic of macrolide group. It has is a wide spectrum of activity against gram-positive and gram-negative bacteria , especially against Mycoplasma spp., Haemophilus spp., Actinomyces spp., Corynebacterium and Pasteurella spp.. The mechanism of its action is to block protein synthesis in bacterial cells by forming a complex with 50S- ribosomal subunits.
The medication is well absorbed from the digestive tract, it penetrates into all organs and tissues of the body, where creates an antibiotic concentration within 48 hours. It quickly enters into the respiratory tissues. Within 6 hours, tilmicosin reaches the required concentration and begins to act on the pathogens in the lung tissue and airspaces bags. The therapeutic effect lasts more than 48 hours.
Mainly excretes from the body unchanged, basically by glomerular filtration, and excretes as unchanged form in the digestive canal with bile, by inactivating the chelating compounds, and then excreted in the faeces.
INDICATIONS
Poultry (broilers, chicks and turkeys): in case of respiratory diseases caused by Mycoplasma gallisepticum, Mycoplasma synoviae, Ornithobacterium rhinotrachealae, Pasteurella multocida and other pathogens susceptible to Tilmicosin.
Pigs: treatment of animals with respiratory diseases caused by Pasterella multocida, Mycoplasma pyopneumoniae, Actinomyces pyogenes and other pathogens susceptible to Tilmicosin.
Calves (less than 3 months old): suffering from respiratory diseases caused by Pasterella multocida, Pasterella haemolitica, Actinomyces pyogenes,Mycoplasma bovis, Mycoplasma dispar and other pathogens susceptible to Tilmicosin.
DOSAGE AND ADMINISTRATION
Orally in the following doses:
Species | Dosage |
Poultry (broilers, chicks and turkeys) | 30 mL per 100 liters of drinking water (75 mg of Tilmicosin to 1 liter of drinking water) for 3 days. The treatment can be repeated later in the case of stressful situations and new cases of infection. |
Pigs | 80 mL per 100 liters of drinking water (200 mg of Tilmicosin per 1 liter of drinking water) during 5 days. |
Calves (less than 3 months old) | With drinking water or milk substitute twice a day at a rate of 6.25 mg of Tilmicosin per 1 kg of body weight (0.25 mL per 10 kg b.w.) for 5 days, or once a day - 12.5 mg of Tilmicosin per 1 kg of body weight (0.5 mL per 10 kg b.w.) for 3 – 5 days |
During the treatment period, animals and poultry should receive only the water that consist the medication as the only source of drinking water. A fresh solution should be prepared every 24 hours.