EFECTVET (cutaneous spray, solution)

Colourless to yellowish liquid with a characteristic odour of its components.

1 ml of the product contains the following active substances:

- fenthion - 2,0 mg;

- α-cypermethrin - 2,0 mg.

Excipients: dimethyl sulfoxide, benzyl alcohol, 1,2-propylene glycol, glycerol, isopropyl alcohol.

ATCvet code QP53, ectoparasiticides, insecticides and repellents.

EFFECTVET is a combination product containing fenthion and α-cypermethrin.

Fenthion is an organothiophosphate insecticide compound group. Its mechanism of action involves blocking the enzyme acetylcholinesterase in the nerve synapses of the parasite, leading to its death. Fenthion poorly penetrates the blood-brain barrier of warm-blooded animals; however, when applied externally, it is absorbed through the skin and enters the bloodstream. Blood-sucking parasites die upon ingestion of fenthion through the blood of treated animals.

α-cypermethrin is a repellent and contact synthetic pyrethroid with a broad spectrum of insecticidal activity. It blocks the transmission of nerve impulses, causing impaired coordination, paralysis, and death of ectoparasites. It is rapidly metabolized and eliminated from the body, and therefore does not accumulate in animal tissues.

Following application to the skin, the active substances enter the bloodstream, accumulate in the epidermis, hair follicles, and sebaceous glands of the animal, and exert prolonged insecticidal and acaricidal activity.

Prevention and treatment of dogs and cats infested with ectoparasites: fleas (Ctenocephalides spp., Pulex irritans); lice (Linognathus setosus); biting lice (Trichodectes canis, Felicola subrostratus); sarcoptoid mites (Notoedres cati, Otodectes cynotis); and ixodid ticks (Ixodes spp., Rhipicephalus spp., Dermacentor spp., Haemaphysalis spp.).

Treat animals outdoors or in well-ventilated areas. To prevent licking of the product, pply a tape muzzle or place an Elizabethan collar around the neck. Before use, shake the bottle thoroughly. Holding the bottle upright, actuate the spray pump and direct the stream of product from a distance of 10–15 cm onto the animal's body against the natural lay of the hair for several seconds, moistening the fur and skin. Covering the animal's eyes, treat the ear pinnae and sternum; apply the product around the eyes and nose using fingertips, then treat the neck, limbs, abdomen, and tail. Apply the product at a rate of 0,5–1,0 ml per 1 kg of body weight, corresponding to 4 to 9 pump actuations for 100 ml bottles or 2–5 actuations for 250 ml bottles. Repeat treatments are recommended every 3–4 weeks; during periods of peak parasite activity, treatments may be performed more frequently.

Avoid contact of the product with the animal's eyes and mucous membranes during application.

When treating long-haired animals, comb the coat with a brush to apply the product directly to the skin. For animals infested with ixodid ticks, apply the product directly onto the tick and the site of its attachment to the skin (one pump actuation). If the tick does not detach on its own within 20–30 minutes, carefully remove it with tweezers.

To prevent reinfestation of animals with ectoparasites, periodically replace or treat bedding at a rate of 4–6 ml (35–52 actuations for 100 ml bottles or 17–26 actuations for 250 ml bottles) per 1 m² of treated surface. Treated bedding may only be used for animals after 3 days.

For notoedric mange, apply the product to affected areas previously cleaned of scabs and crusts, extending treatment onto the surrounding healthy skin by up to 1 cm. Apply the product by lightly moistening the affected areas at a rate of 1 ml (9 actuations for 100 ml bottles or 5 actuations for 250 ml bottles) per 10 cm² of affected area, 2–5 times at intervals of 7–10 days until clinical recovery.

Animals with large affected areas should be treated twice at 1-day intervals, applying the product to the affected areas first on one half of the body, then on the other.

For otodectic mange, clean the inner surface of the ear pinna and the external ear canal of earwax, exudate, and crusts, then spray the product into each ear with 1–2 actuations for 100 ml bottles or 1 actuation for 250 ml bottles. Repeat 2–3 times at intervals of 5–7 days.

To ensure even distribution of the product, fold the ear pinna and massage gently, holding the animal's head still for 5–10 minutes to prevent splashing. Treat both ears.

Do not use in cases of hypersensitivity to the active substance(s) or to any of the excipients.

Do not use in sick, emaciated, or debilitated animals.

Do not use in puppies and kittens under 3 months of age.

Do not use in females during pregnancy or lactation.

Observe standard hygiene and safety rules applicable to the handling of veterinary medicinal products.

Wear rubber gloves when treating animals. Wash hands thoroughly with warm water and soap after use. For 48 hours following treatment, avoid contact between treated animals and children under 2 years of age.

In sensitive animals, transient reactions may occur after treatment (salivation, restlessness), which resolve quickly. In the event of allergic reactions (skin rash, pruritus, oedema), desensitizing therapy is recommended. Antidote: atropine sulphate.

Do not bathe animals for 48 hours before or after treatment.

Polymer bottles with spray cap: 100 ml, 250 ml.

Store in a dry, dark place, out of reach of children, at a temperature of 5–25 °C.

2 years.

After the first opening, the product must be used within 6 months, provided it is stored at a temperature of 5–25 °C.