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| Ingredients: | Fenthion |
| Application: | External use |
| Type of formulation: | Inseсto-acaricides |
CHARACTERS
A yellowish to red-brown, oily liquid with a characteristic odor of thecomponents.
COMPOSITION
1 mL of solution contains:
The active substance:
Fenthion – 30.0 mg;
Excipients:
1.2-propylene glycol, flavor, glycerol,benzene alcohol, isopropyl alcohol.
PHARMACOLOGICALPROPERTIES
ATCvet QP53А, Ectoparasiticides for topical use, incl.insecticides (QP53AF07, Fenthion)
Fenthion is an organothiophosphate insecticide. Themode of its action is blocking acetylcholinesterase (AChE) insynapses of the central nervous system of a parasite this resulting in itsdeath. Fenthion penetratespoorly the hematoencephalic barrier of warm-blooded animals, but, if appliedexternally, is easily absorbed through the skin and enters the blood. Blood-suckingparasites die due to the entry of fenthion into their organism with animals’blood.
INDICATIONS FORUSE
The medicinal product is employed to treat and preventthe infestation of wingless ectoparasite insects (siphonapteroses) in cats: Ctenocephalides felis (the cat flea), Ctenocephalides canis (the dog flea), Pulex irritans (the human flea).
ROUTE OF ADMINISTRATION AND DOSAGE
Before using the medicinal product, cut off thepipette tip with scissors.
Use the medicinal product externally throughapplication to the animal’s skin in the shoulder area and along the backbone atthe following dose level: one 1.0-mL pipette for cats of more than
A single treatment of animals prevents the infestationof ectoparasite insects for 3-6 weeks. Animals are treated repeatedly 3-4 weekslater.
CONTRAINDICATIONS
Hypersensitivity to fenthion.
Do not apply the medicinal product to kittens of up to
Do not use inanimals simultaneously with, or within several days prior to or after, thetreatment or effect of medicinal products that inhibit cholinesterase, suchas carbamates, levamisol, morantel, pyrantel.
Do not use fenthionin animals suffering from diarrhea, chronic constipation, colics, convulsions, breathingtroubles, renal and/or cardiac impairment.
Do notapply the medicinal product to debilitated, sick, and starved animals.
Do not use in females during pregnancy and lactation.
PRECAUTIONS
In sensitive animals after treatment or in animalswhich have licked the medicinal product off immediately after its application, nervousdisorder signs such as, for example, hypersalivation, vomiting, anxiety, abdominaldistention, generalized tremor, generalized tremor, respiratory disturbance, unsteadygait, may occur. These signs disappear in a few minutes with no additionaltreatment. In allergic complications, such as skin rash, itch, andedemas, desensitizingtherapy is recommended. As an antidote, atropine sulfate may be used.
In the event of large damages of skin, a topicaltreatment with fenthion may result in an excessive absorption by the skin withparasympathetic symptoms developed.
Depolarizing neuromuscular relaxants may not be used during10 days after the administration of organic phosphorus substances, for theseenhance side effects.
Do not combine fenthion with neuroleptic agents.
In young animals and pregnant females, use themedicinal product as carefully as possible.
Comply with the basic hygiene and safety rulesaccepted in handling veterinary medicinal products.
Treat animals in the open; when doing so, wear rubbergloves.
Apply the medicinal product to areas inaccessible forlicking off; do allow other animals to lick the medicinal product off.
Do not smoke, do not drink, and do not eat whentreating animals with the medicinal product.
Following the handling the medicinal product, washyour hands with soap and warm water; wash and dry up the gloves. In case ofskin contact or eye contact, immediately wash the skin or flush the eyes withrunning water.
Avoid the medicinal product from contacting theanimal’s eyes. Do not apply the medicinal product to damaged skin and wounds.
After the treatment of animals with the medicinalproduct, do not stroke them and do not allow children to contact them until theanimal’s hairs have been dried fully. Also, after the treatment of animals, theyshould not sleep together with their owners, especially with children.
Clean and treat periodically with the appropriateinsecticides items of care and places of keeping pets, such as litters, carpets,furniture.
HOW SUPPLIED
1.0-mL polymeric dropping ampoules or pipette vials. Secondarypackage: carton.
STORAGE
Store at adry place protected from light at between 5 °С and 25 °С. Keepout of reach of children.
SHELF LIFE
18 months of the date of manufacture.