Baktiofur 20% (suspension for injection)

Baktiofur 20% (suspension for injection)
Ingredients: Ceftiofur
Application: Injection
Type of formulation: Antibiotic

Description

Oily suspension for injections from white to light brown color.

Composition

1 ml of the preparation contains active substance:
free acid of crystalline сeftiofur -200 mg.

Pharmacological properties

ATC vet classification code QJ01 – anti-infective veterinary preparations for system application.
Сeftiofur is a semi-synthetic antibiotic of third generation cephalosporins group. It possesses a wide spectrum of action against gram-positive and gram-negative bacteria (Pasteurella haemolytica (Mannheimia spp.), Escherichia coli, Pasteurella multocida, Haemophilus somnus, Fusobacterium necrophorum and Bacteroides melaninogenicus (Porphyromonas asaccharolytica), Arcanobacterium pyogenes, Fusobacterium necrophorum, Arcanobacterium pyogenes,  Actinobacillus pleuropneumoniae and Streptococcus suis). Сeftiofur inhibits (suppresses) synthesis of cell walls of bacteria, suppressing synthesis of peptidoglycan.
After parenteral administration, сeftiofur is rapidly metabolized into desferalceftiofur, active metabolite. Due to the binding to plasma proteins, active ceftiofur metabolite is concentrated in the site of inflammation.
Maximum concentration of antibiotic in the blood plasma is observed in 12 hours after the preparation administration and remains on the therapeutic level at least 7 days. Сeftiofur is excreted from organism mostly with urine and partially with feces.

Application

Treatment of cattle at respiratory infections of bacterial aetiology caused by microorganisms: Pasteurella haemolytica (Mannheimia spp.), Pasteurella multocida, Haemophilus somnus, for treatment of necrobacillosis caused by bacteria:  Fusobacterium necrophorum and Porphyromonas levii, Bacteroides spp, Prevotella spp, for treatment of puerperal mastitis, which caused by bacteria: Escherichia coli, Arcanobacterium pyogenes and Fusobacterium necrophorum, as well as for mastitis treatment.

Dosin

Subcutaneously at the base of ear, forward in the direction of opposite animal's eye (see the figure) at a dose of 1 ml of the preparation for 30 kg of body mass (6,6 mg of сeftiofur for kg of body mass) once.
Prior to use a vial with the preparation should be thoroughly shaken to homogeneous suspension obtaining and sediment resuspension.
Maximum volume of the preparation for administration into one site must not exceed 30 ml

Contra-indications

Do not apply to animals with increased sensitivity to B-lactam antibiotics.
Do not administer intravenously.

Warning

Slaughter of animals for meat is permitted after 20 days after last application of the preparation. The excretion period for milk is 0 hours.
Obtained before specified period meat is disposed or fed to non-productive animals, depending on conclusion of veterinary medicine doctor.
Application of the preparation should be based on pathogens sensitivity determination as well as taking into account of local rules of antimicrobial preparations application.
Penicillins and cephalosporins can cause reactions of hypersensitivity after injection, inhaling, ingestion or contact with skin. Hypersensitivity to penicillins can cause cross-reactions to сephaIosporins and on the contrary. Allergic reactions to these substances sometimes can be severe.
When application of the preparation in accordance to the package leaflet, side effects and complications are usually not observed. In particular, cases formation of swelling is possible.
Should avoid of accidental administration of the preparation to a human. In case of accidental injection to a human, consult a doctor immediately showing the package leaflet or the preparation label. Working with the preparation to people with increased sensitivity to B-lactam antibiotics is not recommended.
In case of preparation contact with skin, rinse thoroughly with soap and water. In case of contact with eyes rinse with pure water immediately.

Form of presentation

Vials of neutral glass (marks NS-1, NS-2, UPS-1) closed with rubber stoppers under aluminum crimp seal of 10, 20, 50, 100 and 200 ml. Secondary package – cardboard boxes.

Storage

Dry, dark, out of the reach of children place at a temperature from 5°C to 25°C.
Shelf life of the preparation while observing the storing conditions in a closed package is 2 years from the date of manufacture.
After first withdrawal from the vial, the preparation should be used within 14 days, under conditions of storing in a dark place at a temperature from 0 °С to 8 °С.
For applications in veterinary medicine!

Write a review