HEPASAN FORTE (feed additive)

Solution for oral administration

1 ml of the feed mixture contains:

- L-carnitine (3a910)         - 35.0 mg;  

- Betaine hydrochloride (3a925) - 51.54 mg;

- L-arginine (3c362)         - 30.0 mg;

- DL-methionine (3c301)         - 20.0 mg;       

- milk thistle extract (CoE 551)         - 35.0 mg;

- succinic acid (2b08024)         - 5.0 mg;

- sodium benzoate (1k301)         - 0.25 mg;

- purified water.

HEPASAN FORTE feed mix is a hepatoprotector with combined pharmacological properties of its individual components with a pronounced stimulating, protective and choleretic effect on the liver, which improves its function and metabolism, optimizing basic physiological processes.

L-carnitine is a product of lysine and methionine biosynthesis, which accelerates metabolic processes. L-carnitine is involved in the breakdown of excess fatty acids, enhancing their oxidation and transport to mitochondria, plays an important role in the transport of acetyl-coenzyme A, increases the use of energy sources by cells, and helps to normalize metabolism in the body.

Betaine is a natural source of methyl groups and a hepatoprotector, which has a positive effect on metabolism and improves the condition of the intestinal epithelium, ensures more complete absorption of dietary energy, increases resistance to stress, has choleretic and lipotropic effects, activates metabolic methylation in the liver and synthesis of cell membrane phospholipids.

L-arginine - stimulates cellular metabolism, promotes neutralization and excretion of ammonia, regulates blood sugar and reduces lactic acidosis caused by muscle exertion, activates the system of nitrogen-containing enzymes, synthesizes a nitroso group, providing the necessary tone of the arteries. 

DL-methionine is an essential amino acid with metabolic and hepatoprotective effects, is a donor of mobile metal groups, and is necessary for the synthesis of choline, the deficiency of which disrupts the synthesis of phospholipids from fats and the deposition of neutral fat in the liver. It participates in the metabolism of sulfur-containing amino acids, in the synthesis of adrenaline, creatinine and other biologically important compounds, activates the action of hormones, vitamins (cyanocobalamin, ascorbic and folic acids), enzymes, proteins, reduces cholesterol concentration and increases the concentration of blood phospholipids. DL-Methionine prevents excessive accumulation of fat-soluble compounds in liver cells and stimulates rapid elimination of various toxins, including heavy metals, from liver and kidney cells. DL-methionine improves the efficiency of the feed mixture, increases muscle gain, improves the synthesis of adrenaline, creatine and hemoglobin, participates in the synthesis of structural components of protein, vitamins, hormones and enzymes, is suitable for use at all stages of animal and bird development, promotes the proportional development of the bone and muscle skeleton of animals and birds.

Succinic acid increases the digestibility of feed, enhances biosynthesis processes, is a universal anti-stress substance, does not cause xenobiotic effects, improves cellular respiration and metabolism, including glucose, improves the functioning of the respiratory system, kidneys, intestines, and supports the endocrine system. 

Milk thistleextract, obtained from mature fruits of milk thistle (Silybum Marianum L), contains silymarin, a biologically active complex, which is a mixture of flavonolignans.

The hepatoprotective effect of silymarin is due to its antioxidant and membrane-stabilizing properties.

Silymarin prevents the accumulation of lipid hydroperoxides and thereby reduces the degree of liver cell damage. In addition, by stabilizing the cell membrane of hepatocytes, silymarin slows down the intake of toxic substances (both exogenous and endogenous). Silymarin also activates metabolism, which results in normalization of protein-synthesizing and lipotropic functions of the liver.

The use of the feed mixture leads to an increase in the body's endurance, improvement of heart function, reduction of subcutaneous fat, increase in muscle mass due to the acceleration of metabolic processes in cells, improved penetration of vitamins and minerals into cells and elimination of decay products. The feed mixture reduces the risk of fatty liver, nephrosis, myocarditis, prevents stress (thermal, transport, etc.), increases appetite and feed absorption, improves digestion and fat absorption, which is especially important during the period of intensive growth of animals and poultry.

The feed mixture is used to support liver function, detoxification in endo- and exotoxicosis, accelerate hepatocyte regeneration, accelerate recovery during periods of intense stress, normalize metabolism, improve heart function, increase overall resistance and productivity, prevent stress, accelerate growth in calves, goats, sheep, pigs, horses, poultry, rabbits, dogs and cats.

The feed mixture is administered orally to horses, calves, goats, sheep, pigs, poultry, rabbits for 5-10 days and to dogs and cats for 7-10 days in the following doses:

- fattening calves - 0.4-0.5 ml per 1 litre of liquid feed;

- sheep, goats, pigs, horses, rabbits - 0.4-0.5 ml per 1 litre of drinking water;

- poultry - 0.3-0.4 ml per 1 litre of drinking water;

- dogs, cats - 0.1 ml (approximately 2-3 drops) of the feed mixture per 1 kg of animal body weight per day, administered orally, directly to the animal or mixed with food or drinking water, for 7-10 days. 

In case of liver damage due to babesiosis and leptospirosis, the dose may be increased to 0.3 ml of the feed mixture per 1 kg of animal body weight per day.

The duration of treatment may be extended by a veterinarian's decision.

In case of increased physical activity, the dose for dogs may be increased to 1.0 ml of the feed mixture per 1 kg of body weight.

Increased individual sensitivity to the components of the feed mixture.

When working with the feed mixture, it is necessary to comply with generally accepted sanitary and hygienic standards and rules at work.

Do not mix with vaccines administered with water.

Polymer vials (canisters) of 1, 5, 10, 20, 25 liters.

Neutral glass vials NS-1, NS-2, USP-1, 10, 20, 30, 50 and 100 ml each. 

Store in a dry, dark place at temperatures between 5 and 25°C.

2 years. 

The shelf life after the first opening of the primary container, subject to storage conditions, is 28 days.

Vetsintez Limited Liability Company 

30 Smolna St., Kharkiv, 61001, Ukraine