DESCRIPTION
Oily, transparent liquid with light-yellow to yellow color, with specific odor of the components.
COMPOSITION
PHARMACOLOGICAL PROPERTIES
ATC vet classification code QJ01- antibacterial veterinary medicines for systemic use. QJ01FA90 - Tylosin.
Tilosin – macrolide antibiotic, active against the gram-negative and gram-positive microorganisms (Staphylococcus spp., Streptococcus spp., Diplococcus spp., Corynebacterium spp., Clostridium spp., Erysipelothrix rhusiopathiae, Neisseria spp., Bacteriodes nodosus, Moraxella bovis, Pasteurella spp., Spirocheta spp.). Particularly sensitive to tilosin mycoplasmas (Mycoplasma gallisepticum, Mycoplasma hyopneumoniae, Mycoplasma synoviae, Mycoplasma meleagridis, Mycoplasma agalactiae, Mycoplasma bovigenitalium), and also chlamydias and rickettsia.
The mechanism of action of the preparation is to block protein synthesis in bacterial cells by forming a complex with the 50S – subunits of ribosomes.
INDICATIONS
Cattle: treatment from gastroenteritis, diphtheria, necrotic pododermatitis, metritis, mastitis, arthritis and pneumonia caused by micro-organisms sensitive to tylosin.
Sheep, goats: treatment from bronchopneumonia, interstitial pneumonia, pleuropneumonia, contagious ahalaktis, chlamydial abortion micoplasmatic arthritis caused by microorganisms sensitive to tylosin.
Pigs: treatment from enzootic bronchopneumonia, erysipelas, dysentery, leptospirosis, MMA syndrome, atrophic rhinitis, micoplasmati and staphylococcal arthritis caused by microorganisms sensitive to tylosin.
Dogs: treatment from pneumonia, rhinitis, laryngitis, tonsillitis, bronchitis, otitis media, eczema, cystitis, metritis, biogenic dermatitis, leptospirosis, caused by pathogens sensitive to tylosin.
DOSAGE
Intramuscularly, once a day in following doses:
- cattle – 0.25 ml of the preparation per 10 kg of body weight;
- sheep, goats – 0.5 ml of the preparation per 10 kg of body weight;
- pigs – 0.5 ml of the preparation per 10 kg of body weight;
- dogs – 0.1 - 0.5 ml of the preparation per 10 kg of body weight.
Treatment course: 3 – 5 days.
CONTRAINDICATIONS
PRECAUTIONS
Animals may only be slaughtered for meat not earlier than 21 days after the last treatment and for milk– 4 days.
HOW SUPPLIED
Neutral glass vials of 10-mL, 20-mL, 50-mL,100-mL and 200 mL, closed by a rubber stopper and sealed with an aluminum cover. Secondary package: carton box.