IVERMECVET 1% (solution for injection)

Oily liquid from colourless to slightly yellow.

1 ml of the product contains active substance:

- ivermectin – 10.0 mg.

Excipients: benzyl alcohol, 1,2-propylene glycol.

ATC vet QP54, endectocides (QP54AA01, ivermectin).

The active ingredient of the product is ivermectin, which belongs to compounds produced by the actinomycete bacterium Streptomyces avermitilis. The mechanism of action of the product on parasites is that ivermectin stimulates the release of gamma-aminobutyric acid (GABA), which binds to specific receptors on nerve endings, increases membrane permeability to chloride ions and blocks the transmission of neuromuscular impulses, leading to paralysis and death of the parasite.

IVERMECVET 1% has high efficacy and a broad spectrum of activity (insecticidal, acaricidal and nematocidal activity against adult and larval stages of parasite development) and relatively low toxicity for warm-blooded animals.

After parenteral administration the product is rapidly absorbed from the injection site and distributed in the organs and tissues of animals, providing parasiticide action for 10-14 days. It is excreted from the animal body with urine and bile, and in lactating animals also with milk.

At the recommended doses the product does not have embryotoxic, teratogenic or mutagenic effects.

For the treatment and prevention of diseases in cattle, sheep, goats and pigs caused by:

- gastrointestinal and respiratory nematodes (adult and larval stages) – Ostertagia spp., Haemonchus placei, Thelazia rhodesi, Cooperia spp., Trichostrongylus, adult stages of Dictyocaulus viviparus, Nematodirus spp.;

- warble flies Hypoderma bovis, H. lineatum;

- sarcoptic mites Psoroptes bovis, Sarcoptes bovis;

- lice Haematopinus eurysternus.

- gastrointestinal and respiratory nematodes (adult and larval stages) – Ostertagia spp., Haemonchus contortus, Trichostrongylus spp., Cooperia spp., Oesophagostomum spp., Nematodirus spp., Chabertia ovina, Trichuris ovis;

- adult and larval stages (4th stage) of Dictyocaulus filaria, Protostrongylus spp.;

- sarcoptic mites Sarcoptes ovis;

- sheep ked Melophagus ovinus.

- gastrointestinal nematodes (adult and larval stages) – Ascaris suum, Hyostrongylus rubidus, Oesophagostomum spp., only adult stages – Strongyloides ransomi;

- as well as respiratory nematodes (only adult stages) Metastrongylus spp.;

- lice Haematopinus suis;

- sarcoptic mites Sarcoptes suis.

Single administration at the following doses:

- cattle – 1,0 ml of the product per 50 kg body weight, subcutaneously in the shoulder area;

- sheep, goats – 0,5 ml of the product per 25 kg body weight, subcutaneously;

- pigs – 1,0 ml of the product per 33 kg body weight, subcutaneously in the neck region.

It is necessary to carefully calculate doses of the product for pigs weighing up to 16 kg.

In the treatment of severe forms of sarcoptic mange, the treatment is carried out twice with an interval of 7 days.

When administering the product at a dose exceeding 10 ml, injections should be carried out at several sites.

Each batch of the product is preliminarily tested on a small group (7-10 head) of animals. In the absence of complications within 2-3 days, treatment of the whole herd is started.

Painfulness at the injection site is possible. Sometimes allergic reactions (skin rash, itching and swelling) may occur. In such cases, desensitizing therapy is prescribed.

Hypersensitivity to ivermectin.

Do not use in sick, emaciated and weakened animals.

Do not use in animals with liver and kidney diseases.

Do not administer to dairy animals whose milk is intended for human consumption.

Slaughter of animals for meat is allowed: cattle, sheep, pigs – 49 days after the last administration of the product.

Do not administer to cows during lactation and during the last month of pregnancy (28 days before calving).

Do not use simultaneously with other anthelmintic products.

Ampoules made of neutral glass grade NS-1, NS-2, USP-1 of 1 ml. Vials made of neutral glass grade NS-1, NS-2, USP-1, closed with rubber stoppers under aluminum caps of 10; 20; 50; 100 ml. Secondary packaging – cardboard box.

Store in a dry, cool place protected from light at a temperature from 10 to 25 °C in the manufacturer’s container (according to List B (national classification)) on shelves or in tiers (not more than three).

1 year from the date of manufacture, provided that the conditions of transportation, storage and use are observed.