| Ingredients: | NOSIHEPTIDE |
| Application: | Orally |
| Type of formulation: | Antibiotic |
DESCRIPTION
Granulated powder, ranging in color from grayish-white to brown.
COMPOSITION
1 g of the product contains the active ingredient:
- Nozigeptid – 10.0 mg
Excipients: Calcium carbonate.
PHARMACOLOGICAL PROPERTIES
ATC vet classification code QA07A – Antimicrobial veterinary medicines used for intestinal infections.
The active ingredient, Nozigeptid, is an antibiotic from the polypeptide group. It has a bactericidal effect on gram-positive microorganisms, such as Clostridium perfringens, Streptococcus spp., Staphylococcus spp., as well as on some gram-negative microorganisms, such as Pasteurella multocida and Neisseria catarrhalis.
The mechanism of action of the antibiotic involves disrupting bacterial protein synthesis, particularly by acting on the 50S ribosomal subunit, strongly binding the 23S rRNA complex with the ribosomal protein L11.
Bacterial resistance to Nozigeptid develops slowly, and resistance has not been observed in Clostridium perfringens. No cross-resistance to Nozigeptid has been found in microorganisms with other antibacterial drugs.
Nozigeptid is not absorbed from the gastrointestinal tract, so it acts solely on the intestinal flora. A high concentration of Nozigeptid is maintained in the gastrointestinal tract, providing a prolonged antibacterial effect. It does not accumulate in tissues and is excreted unchanged with feces.
INDICATIONS
For the treatment of pet birds (canaries, parrots, pigeons) suffering from gastrointestinal diseases, including necrotic enteritis caused by microorganisms sensitive to Nozigeptid.
DOSAGE AND ADMINISTRATION
Orally with feed at the following doses:
Canaries, parrots, pigeons: 0.2–0.25 g of the product per 1 kg of feed for 5–7 days.
The medicated feed should be the only source of food during the entire course of treatment.
If necessary, the treatment course can be repeated.
CONTRAINDICATIONS
Hypersensitivity to Nozigeptid.
Not for use in productive animals.
PRECAUTIONS
Interactions with other products:
Do not administer simultaneously with strong oxidizers.
Special precautions for users and staff:
Follow standard hygiene and safety rules when handling veterinary medicines. Work should be performed using appropriate protective clothing and personal protective equipment. In case of accidental contact with the skin or mucous membranes, rinse immediately with running water. If the product comes into contact with the eyes, rinse with plenty of water and seek medical attention.
FORM OF RELEASE
Polyethylene bags containing 1, 10, 50, or 100 g.
STORAGE
Store in a dry, dark place, out of reach of children, at a temperature between 5°C and 30°C.
SHELF LIFE
2 years.