BAXINOL
Composition:
1 g of the additive contains (mg):
formic acid (E236) - 570;
propionic acid (E280) - 150;
propionate calcium (E282) - 100;
lactic acid (E270) - 100;
citric acid (E330) - 25;
acetic acid (E260) - 10;
succinic acid - 5.
Additive: purified
water - up to 1000 mg.
Pharmaceutical form and presentation
Solution.
Pharmacological properties
Food additive BAXINOL is a balanced combination of synergizing acting organic acids
that has cumulative properties of acidifying agent
and conserving agent in fodders and potable water BAXINOL assists in
stabilization of microflora of animals and poultry alimentary canal,
inhibits growth and progress of bacterial species Е.соlі, Salmonella, Campilobacter, Pseudomonas etc., yeast fungi
in fodders, water and alimentary canal of animals and poultry. Maintains nutritional properties and
increases the shelf life of fodders. PH decrease assists in proteins
assimilation and ferments activation and makes better digestion process.
Creates favourable conditions for growth of useful microflora. Decreases pH of potable water and
cleans a water feed system from biofilm and prevents its formation.
BAXINOL decreases the level of water bacterization by pathogenic microorganisms
(formic and acetic acids), inhibits its progress in intestines, prevents
development of diseases of alimentary canal of poultry and pigs, has an
anti-fungal effect (propionic acid and its salts, lactic acid). Decreasing pH
level in intestines the additive creates optimal conditions for development of
propionic and lactic acid bacteria and inhibits reproduction of pathogenic
microflora. Unionized forms of organic acids are lipophilic, therefore, they
penetrate through the membrane of bacterial cells, disturb their metabolism and
DNA replication and cause bacteriostatic effect.
Formic acid decreases pH level and buffer capacity of fodder inhibiting
the growth and progress of pathogenic bacteria: Е.соlі, Salmonella, Campilobacter, Pseudomonas etc. and also
increases assimilation of calcium and phosphor. Among carboxylic acids formic
acid has the most evident antibacterial effect.
Propionic acid and its salt have a strong anti-fungal effect. Propionic
acid is absorbed through alimentary canal and transported to the liver where
propionate is completely changed into glucose. In combination with formic acid
these acids have synergetic effect and used against some gram-positive
causative agents (Clostridium).
Lactic acid actively stimulates ferments secretion of pancreas. It
simultaneously creates favourable conditions for development of Lactobacillus bacteria that stop the
growth and progress of pathogenic micro organisms of small intestine part of
animals. Lactic acid stimulates renewal of intestinal villi that increase the
surface of nutritive absorption. Lactic acid has a preventive effect to
mycotoxins - aflatoxins (fungus: Aspergilus
flavus, A parasiticus), improves fodders tastiness.
Citric acid is an effective anti-stress component that stimulates
formation of chelate forms of calcium, potassium, ferrum, zinc and any other
micro elements in intestines as a result of what they are better ingested by an
organism. Citric acid neutralizes radionuclides, pesticides and it is an
universal antioxidant that prevents oxidation of fats and spoilage of fodders.
Acetic acid is a catalyst for protein cleavage into amino acids and has
a strong bactericidal action.
Succinic acid increases fodder digestion, biosynthesis processes, is an
universal anti-stress substance, does not cause any xenobiotic effect, increases
cell breathing and metabolism including glucose, improves functioning of
respiratory organs, kidneys, intestines, maintains endocrine system
functioning.
Organic acids decrease buffer capacity of fodder alkaline components
that stimulate nitrogen and fodders macro elements use, increase ferments
secretion in stomach, pancreas and intestines, transformation of nutritive
materials, stimulate growth of intestinal villi what makes better parietal
digestion and increases absorption of nutritive materials, prevent such
diseases as enteritis, decrease intensity of fermentation process in the part
of large intestine.
Clinical particular features
Animal species
Pigs, poultry (laying hens, broilers, chicks, replacement chicks).
Indications
Protection
of fodders and potable water against pathogenic microflora, conservation,
fodders acidification that assists in increase of fodders shelf life,
acidification of animals and poultry alimentary canal that assists in
inhibition of progress of gram-negative and putrefaction micro organisms in
alimentary canal, improvement of fodders digestion process, absorption of
fodder nutrients, stimulation of growth and increase of poultry and pigs’
productivity.
We recommend to use BAXINOL after the use of antimicrobial
preparations, especially for prevention of colibacillosis, clostridiosis and other
diseases.
Contraindications
N/A
Special precautions during use
N/A.
Use during pregnancy, lactation and carrying
According to the recommended dosage.
Drug-to-drug interactions and other forms of interactions
N/A.
Dosage and administration route for animals of different age
BAXINOL shall be sprayed on fodder
during mixing or fed together with fodder by means of stage-by-stage mixing or
added in potable water on the basis of:
fodder for pigs - 1-2 l of additive per
1000 kg;
fodder for poultry - 1-3 l per 1000 kg;
potable water - 0.3-1 l / 1000 l;
For cleaning of a water feed system: 0.5% solution shall be added to the
system and kept during 12 hours. After use it shall be flushed by cold water;
For salmonellosis disease prevention the feed additive shall be added to
the fodder or water on the basis of: 0.1-0.3% from fodder volume.
The dose depends
on the level of the bacterial background, fodder composition and potable water
quality.
The max. efficiency of the feed
additive is when pH of water is 4.2-4.6 (you shall control the pH level of
water).
Special warnings and precautions for persons and maintenance staff
Detrimental
to health in case of inspiration and contact with skin! You shall avoid
contacts with skin, eyes and clothes. Do not inhale vapours! Use protective
clothes, masks, gloves and safety goggles during the work. Wash throughly the
hands with water after the work with the product. High concentrated mixture.
Store the feed additive in the tightly closed package, be careful during
opening.
The
appropriate ventilation of the premise shall be provided during the work with
the feed additive. Use protective clothing, safety goggles, protective gloves
and mask. In case of contact with skin you shall immediately wash it by use of
large volume of water and soap. In case of contact with eyes you shall
immediately wash them with water during several minutes, if any contact lenses
are present you shall take them away and continue to wash the eyes with water.
In case of accident after inspiration you shall bring the injured person in the
open air and keep him or her in the position convenient for breathing. You
shall seek medical advice if you feel any indisposition. Unused feed additive
and its rests shall be utilized according to the regulations of the effective
legislation.
Pharmaceutical particular features
Shelf life
Shelf life is 2 years.
The shelf life after the first opening
of the original package in case of following the storage conditions and the
subsequent hermetic closing of the package with the feed additive is 3 months.
Special measures for storage
Store in a dry
and dark place at the temperature of 5 -25 °С.
Nature and
content of the original package container
Small bottles of neutral glass of NC-1,
NC-2, UCP-1 series closed by rubber plugs under aluminium rolling with weight
of 50 and 100 g.
Polymeric containers (canisters) 1; 5; 10;
20 and 25 kg each or in bulk.