CHARACTERS
A brown-colored liquid with a characteristic odor of
the components; precipitation is tolerable.
COMPOSITION
Phenibut -
100,0 mg.
Excipients: Dry extract of
valerian root; dry extract of mint; dry extract of motherwort, dry extract of
hop strobiles, dry extract of juniper; sodium benzoate, sucralose, glycerol, flavor,
purified water.
PHARMACOLOGICAL PROPERTIES
АТСvet code: QN06BX, Other psychostimulants and
nootropics. QN06BX22, Phenibut.
Phenibut is a phenyl derivative of gamma-aminobutyric acid (GABA) and phenylethylamine, aminophenylbutyric acid hydrochloride. By strengthening inhibitory GABAergic processes, it affects the
functional state due to the normalization of metabolism and effects on cerebral
circulation through increase in the
blood flow velocity and a reduction in vascular tone. Phenibut has a pronounced stress-correcting effect, provides
the normalization of the processes of excitation and inhibition in the central
nervous system. The medicinal product is
also used to prevent kinetosis (airsickness syndrome).
The complex of herbal
substance extracts enhances the sedative effect of the medicinal product;
promotes to a reduction in great tonicity, in fear, to the improvement of
restorative and adaptive processes, to the elevation of resistance to exposure
to unfavorable environmental factors.
In terms of the
degree of effect on the organism, the medicinal product belongs to low-hazard
substances. If used at the recommended doses, it exerts no mutagenic,
carcinogenic or sensibilizing effect.
INDICATIONS FOR USE
The medicinal product is used in dogs to reduce
excitation and to correct psychogenic disturbances of behavior in stresses,
phobias, aggression behavior with no single triggering event and in the event
of elevated sexual excitement (in combination with contraceptive agents).
The medicinal product is used to improve restorative and adaptive
processes of the animal’s
organism, to elevate resistance to exposure to unfavorable environmental
factors.
The medicinal product is
also used to prevent kinetosis (airsickness syndrome).
ROUTE OF ADMINISTRATION AND DOSAGE
Administer to dogs orally in a forced onto the tongue
root, into cheek pouches or combined with a small quantity of sweets taking the
body weight, nervous state, and excitation degree of the animal into account at
the following daily doses:
Dogs (adult animals): 2 drops (0,1 mL) of the medicinal product (equipment to
10 mg of phenibut) per
Puppies: 1 drop (0,05 mL) of the medicinal product (equipment to 5 mg of
phenibut) per
Divide the daily dose of the medicinal product into
two intakes and administer in the morning and in the evening.
The course of treatment is 15 to 20 days.
If there are
signs of severe excitation and psychogenic behavioral disorders such as
aggression, fear, hyperactivity, excessive vocalization or hypervocalization
(barking), hypersexual behavior, urinary marking, the course of
treatment may be extended up 4 weeks.
With the re-manifestation in animals of signs of
behavior disorders, repeat the course of treatment with the medicinal product
at the same doses using the same route of administration.
In order to
prevent stresses (transportation, guest arrival, change of scenery, departure
of the owner, intensive training, participation in shows and competitions), use
the medicinal product 3 to 5 days before the expected event and for 1 to 4 days
after its completion.
To prevent
airsickness, use the medicinal product once at the above doses 1 to 2 hours
before an expected beginning of transportation of the animal. When expressed
manifestations of airsickness (vomiting) appear, the intake of the medicinal
product is of low efficacy.
To correct
behavior in case of increased sexual activity, administer the medicinal product
at the same doses in combination with contraceptive agents. The duration of the
course of treatment depends on the individual sensitivity of the animals and
the degree of their excitement.
CONTRAINDICATIONS
Individual hypersensitivity to any of the medicinal
product components including in past medical history.
Do not administer to animals suffering from
genitourinary system disorders, cancers, and diabetes.
Do not use the medicinal product in pregnant and
lactating females.
PRECAUTIONS
If the medicinal product is used for the first time,
drowsiness or excitation, irritability, nausea, allergic reactions have been
rarely reported. In such events, terminate using the medicinal product and
prescribe symptomatic and desensibilizing therapy.
If combined with tranquilizers, neuroleptics, and
anticonvulsants, the medicinal product potentiates and extends the action of
the latter.
Drowsiness or excitation, irritability, nausea,
allergic reactions have been rarely reported in some animals. In such events,
terminate using the medicinal product and prescribe symptomatic and
desensibilizing therapy. The recommended doses should be used.
HOW SUPPLIED
10-mL or 15-mL polymeric or glass vials put into
cardboard packs along with a syringe dispenser.
STORAGE
Store at a dry place protected from light at between 5
°С and 25 °С. Keep out of reach of children.
SHELF LIFE
2 years.