Amprolinvet (oral solution)

Amprolinvet (oral solution)
Amprolinvet (oral solution)
Ingredients: Amprolium Hcl
Application: Oral
Type of formulation: Coccidiostatic

DESCRIPTION

Oily liquid from light to dark yellow color.

COMPOSITION

Each 1 ml contains:
active substance:
amprolium hydrochloride – 125 mg.

PHARMACOLOGICAL PROPERTIES

ATCvet QP51A, preparations against protozoan infections (QP52AX09, amprolium).

Active working substance of the preparation – amprolium hydrochloride, has a wide range of anticoccidioidal action, is effective against coccidia of chickens E. tenella, E. necatrix, E. acervulina, E. praecox, E. maxima, E. brunette, E. mitis; Turkeys - E. adenoeides, gappapavonis E., E. meleagrimitis; pheasants - E. phasiani, E. colchici, E. duodenalis; rabbits - E. stiedae, E. perforons, E. magna; Lambs - E. arloingii, E. Ahsata, E.faurei; calves - E. bovis and E. zurnii.

Anticoccidioidal action of amprolium is caused by its chemical structure similar to thiamine (vitamin B1), which required for life of eimeria. In the cells of parasites, amprolium violates carbohydrate metabolism, which leads to their death.

It is known that amprolium hydrochloride mainly inhibits the development of eimeria on the stage of shizogony of the first and second generation and is an antagonist of vitamin B1. Almost does not penetrate the cell membrane of the intestinal mucosa of birds and mammals, and is practically non-toxic in therapeutic doses. Most part of amprolium (up to 97%) is excreted from the organism unchanged. The preparation does not inhibit the formation of anticoccidioidal immunity, compliant with vitamins and feed additives used in poultry farming.

Refers to low-toxic compounds.

INDICATIONS

Prevention and treatment of cattle (calves), sheep (lamb), rabbits (rabbits up to 4-5 months old), chickens, turkeys and pheasants with Eimeria lesions:

cattle (calves) – E. bovis and E. Zurnii;

sheep (lambs) – E. arloingii, E. ahsata, E. Faurei;

rabbits – E. stiedae, E. perforons, E. magna;

chickens – Eimeria teneila, E. necatrix, E. acervulina, E. praecox, E. maxima, , E. brunetti, and E. mitis;

turkeys – E. adenoeides, E. gallapavonis, E. meleagrimitis;

pheasants – E. phasiani, E. Colchici, E. duodenalis.

DOSAGE

The preparation is fed with drinking water in the following doses:

Broilers:

prophylactically – 1 ml of the preparation per 1 liter of drinking water (125 mg of amprolium HCl to 1 liter of water) starting from age of 3 – 5 days during the period of raising, excluding from the diet 3 days prior to slaughtering; treatment - 2 ml of the preparation per 1 liter of drinking water (250 mg of amprolium HCl to 1 liter of water) for 5-7 days.

Young chickens:

prophylactically – 1 ml of the preparation per 1 liter of drinking water (125 mg of amprolium HCl to 1 liter of water) starting from the age of 3 – 5 days up to 16 weeks old; treatment – 2 ml of the preparation per 1 liter of drinking water (250 mg of amprolium HCl to 1 liter of water) for 5-7 days.

Turkeys and pheasants:

prophylactically - 1 ml of the preparation per 1 liter of drinking water (125 mg of amprolium HCl to 1 liter of water) starting from the age of 1day up to 12 weeks or before the end of period during which there is a threat of coccidiosis; treatment - 2 ml of the preparation per 1 liter of drinking water (250 mg of amprolium HCl to 1 liter of water) for 3-5 days.

Rabbits:

prophylactically- 2.5 ml of the preparation /10 kg of body weight during a period when there is a threat of coccidiosis; treatment – 5 ml of the preparation /10 kg of body weight for 3-5 days.

Calves under 1 year old and lambs:

prophylactically - 1 ml of the preparation / 10 kg of body weight during a period when there is a threat of coccidiosis; treatment - 2 ml of the preparation / 10 kg of body weight for 5-7 days.

After dilution in drinking water preparation is suitable for use within 16 hours.

CONTRAINDICATIONS

Do not use for animals and poultry with high sensitivity to amprolium hydrochloride.
Do not use during pregnancy, lactation and egg production.
Do not use for weakened, exhausted and sick animals and poultry.

PRECAUTIONS

Animals and poultry may only be slaughtered for meat after 3 days after the last treatment.
Eggs are allowed for human consumption after 10 days of the last treatment.

HOW SUPPLIED

Neutral glass ampoules of 0,5 and 1 ml and flacons of 100 and 1000 ml.
Flacons of neutral glass plugged with rubber plugs at run-aluminum 50 and 100 ml. Outer packaging – cardboard box.
Polymeric containers (bottles) in 500 ml and 1 liter.

STORAGE

In the manufacturing container in a dark, dry place, at 5ºС – 25ºС. On racks or above each other  (max. of three).
Keep out of reach of children.
Shelf life: 2 years.

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